Editorial & Publishing Policies

Aim and Scope

Pathobiology of Aging and Age-related Diseases (PBA) is a new journal on the pathological progression and intervention of aging and age-related disease phenotypes in mammalian species, providing an opportunity to communicate pathology data as a primary scientific focus of aging. Data describing the pathological features of aging and the diseases generally associated with aging have unique challenges. By design, pathology covers a wide range of disciplines, and has an underlying focus of addressing mechanisms using a pathological basis to define the progression of age-associated lesions. These types of data are by nature highly descriptive and informative. The emerging field of aging research has created a need for dissemination of this type of information, especially in mammalian model organisms and humans.

PBA is interdisciplinary in nature and covers all aspects of pathology of aging related to disease phenotypes including cancer, cardiovascular disease, neurological disorders, metabolic dysfunction, renal and gastrointestinal disorders, endocrine dysfunction, musculoskeletal conditions and skin disorders. The underlying theme is based on the sound scientific principles of the pathogenesis of aging and age-related diseases as well as intervention data with resolution of pathological endpoints.

The pursuit of investigations into the science of aging is designed to understand why cellular processes begin to fail with advancing age, and what molecular events contribute to this failure. Pathology is the study of the events associated with the gross, histological, and cellular conditions considered abnormal. In this regard, the pathobiology of aging and age-related diseases is an entity that fits nicely under the pathology umbrella, with the integration of physiology and anatomy as key components to a comprehensive assessment of abnormal versus normal.

We hope to enlighten the scientific community by recognizing outstanding pathology-based scientific contributions in PBA, and allowing scientists to communicate data that might be of less interest in other journals more focused on generic aging or specific scientific disciplines. We will only publish manuscripts that meet the highest standards of science, but the nature of our journal will allow highly detailed and image intensive descriptions of the pathology of aging and disease conditions generally associated with aging. In this regard, technical reports and case studies will be welcome. We are especially interested in developing a focus for advancing the pathological basis of aging in mammalian systems, especially the mouse and humans.

The emphasis will be on preclinical studies as well as clinical studies related to strategies developed in animal models and will be image intensive. Papers on the basic biology of aging in invertebrates will not be considered unless comparative mammalian data is also included.


  • Research papers
  • Review articles
  • Brief reports
  • Case reports
  • New animal models
  • Technical reports
  • Commentary
  • PhD Summaries

Target groups

  • Anatomical and molecular pathologists
  • Gerontologists
  • Geriatricians
  • Transgenic mouse geneticists
  • Toxicologists
  • Scientists, veterinarians and physicians focused on basic and clinical research in cardiovascular disease, cancer, gastrointestinal disease, endocrine disorders, metabolic dysfunction, renal disease, neurological disorders including Alzheimer’s disease, skin disorders, and musculoskeletal disease.


Section Policies


Unchecked Open Submissions Checked Indexed Checked Peer Reviewed

Review articles

Unchecked Open Submissions Checked Indexed Checked Peer Reviewed

Research papers

Unchecked Open Submissions Checked Indexed Checked Peer Reviewed

Brief reports

Unchecked Open Submissions Checked Indexed Checked Peer Reviewed

Case reports

Unchecked Open Submissions Checked Indexed Checked Peer Reviewed

Animal Model Brief

Unchecked Open Submissions Checked Indexed Checked Peer Reviewed

Special issue on Inflammation in Aging and Age-related Diseases

Unchecked Open Submissions Checked Indexed Checked Peer Reviewed

New animal models

Unchecked Open Submissions Checked Indexed Checked Peer Reviewed

Technical reports

Unchecked Open Submissions Checked Indexed Checked Peer Reviewed


Unchecked Open Submissions Checked Indexed Unchecked Peer Reviewed

PhD Summaries

Unchecked Open Submissions Checked Indexed Checked Peer Reviewed

Peer Review Process

Papers submitted to Pathobiology of Aging and Age-related Diseases are subject to rigorous peer review so as to ensure that the research published is 'good science'.

All articles go through a preliminary review by the Editor-in-Chief. When articles are felt to not be appropriate for full peer review, authors are notified at that point, usually within approximately two weeks. Articles that are felt to be appropriate for full review are assigned to at least two peer referees.

Manuscripts are sent out for review electronically, and all correspondence takes place via e-mail. Pathobiology of Aging and Age-related Diseases adheres to a 'double blind' review process: Authors are not told who reviewed their paper, and reviewers are not told who wrote the paper. Peer reviewers are informed of the identity of the authors immediately after the manuscript is either accepted or rejected. The referees’ identity remains unknown to the authors although it is up to the referee if he/she wants to contact the author at a later stage and reveal his/her identity.

Peer reviewers are asked to give their opinion on a number of issues pertinent to the scientific and formal aspects of a paper, and to judge the papers on grounds of originality and urgency. All relevant information will be forwarded to the author(s).

Peer reviewers will have six possible options, for each article:

  1. Accept manuscript (i.e. no need for any revision)
  2. Accept after revision (i.e. accepted if the author makes the requested revisions)
  3. Revise and resubmit (i.e. accepted or rejected after revisions have been made - paper will be sent out for another peer review round)
  4. Submit elsewhere (i.e. if the manuscript is better suited for another journal)
  5. Reject manuscript (i.e. if the manuscript is substandard)
  6. See comments (i.e. if the reviewer cannot choose from any of the above)


When asking for revisions, reviewers have two possible goals: to ask authors to tighten their arguments based on existing data, or to identify areas where more data are needed. Even formal revision may be required if the language or formalities is sub-standard. To facilitate rapid publication, authors are given a maximum of 2 months for revision. After 2 months, revised manuscripts will be considered new submissions.


Publication Frequency

All articles published in Pathobiology of Aging & Age-related Diseases are posted online immediately as they are ready for publication, i.e. after final proofreading. The journal does not collate numbered issues published regularly, but all articles will be assigned a DOI number (Digital Object Identifier) whereby they become searchable and citeable without delay.


Open Access Policy

Open Access
Pathobiology of Aging & Age-related Diseases is published under the terms of the Creative Commons Attribution-Noncommercial 4.0 Unported License.  Authors retain the full copyright to their work. For more information see the copyright section.

Articles are published immediately upon the final corrections of the master proof having been made. All articles are assigned a DOI number (Digital Object Identifier). 

Pathobiology of Aging & Age-related Diseases is accessible via the journal’s website at http://www.pathobiologyofaging.net as well as via international search engines such as Google and Google Scholar.

OAI metadata harvesting for this journal can be reached via the following link:




This journal utilizes the LOCKSS system to create a distributed archiving system among participating libraries and permits those libraries to create permanent archives of the journal for purposes of preservation and restoration. In addition, all files will be archived with PubMed Central, CLOCKSS and Portico.


Author Self-Archiving

Authors are permitted and encouraged to post any version of their manuscript to personal or institutional websites, in repositories and similar, prior to and after publication (while providing the bibliographic details of that publication).